Chemical mutagenesis.
نویسندگان
چکیده
منابع مشابه
Chemical mutagenesis: From plants to human
Following the discovery that chemicals, like ionizing radiation, can induce mutations in Drosophila in the 1940s, work on chemical mutagenesis was started in many parts of the world. At the Botany Division of Indian Agricultural Research Institute, chemical mutagenesis studies in crop plants were initiated by M. S. Swaminathan in the 1950s. This brief review deals with progress of chemical muta...
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Whole-genome sequencing is a useful approach for identification of chemical-induced lesions, but previous applications involved tedious genetic mapping to pinpoint the causative mutations. We propose that saturation mutagenesis under low mutagenic loads, followed by whole-genome sequencing, should allow direct implication of genes by identifying multiple independent alleles of each relevant gen...
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ورودعنوان ژورنال:
- Science
دوره 163 3873 شماره
صفحات -
تاریخ انتشار 1969